Angiotensin Receptor-Neprilysin Inhibitor

ARNI stands for Angiotensin Receptor-Neprilysin Inhibitor. It is a type of medication used primarily to treat heart failure. ARNI combines two components: an angiotensin receptor blocker (ARB) and a neprilysin inhibitor. The ARB helps relax blood vessels by blocking the effects of angiotensin II, a hormone that can cause blood vessels to constrict. The neprilysin inhibitor works by preventing the breakdown of certain peptides that help reduce blood pressure and volume.

Together, these actions help improve heart function and reduce the symptoms of heart failure. One well-known ARNI medication is sacubitril/valsartan, marketed under the brand name Entresto. Always consult a healthcare professional for more detailed information and advice regarding ARNI and its use in heart failure treatment.